Functional Connectivity Driven by External Stimuli in a Network of Hierarchically Organized Neural Modules
نویسندگان
چکیده
Complex neural modules with embedded neural development and synaptic plasticity features have been connected to form a hierarchical recurrent circuit. Virtual electrodes have been used to record a “neural” generated signal, called electrochipogram EChG, from each module. The EChG are processed by frequency domain methods to determine the modifications in functional connectivity by assessing quadratic phase coupling. The experimental paradigm is aimed to describe what happened prior to, at the beginning, towards the end, and after repeating an external input at fixed frequency. The results are discussed by comparing with the same signal processing methods applied to a human study.
منابع مشابه
Functional interactions in hierarchically organized neural networks studied with spatiotemporal firing patterns and phase-coupling frequencies.
A scalable hardware/software hybrid module--called Ubidule--endowed with bio-inspired ontogenetic and epigenetic features is configured to run a neural networks simulation with developmental and evolvable capabilities. We simulated the activity of hierarchically organized spiking neural networks characterized by an initial developmental phase featuring cell death followed by spike timing depend...
متن کاملDetection De Patterns D'activite Bioelectrique Simulee Et Modelisation De Reseaux Neuraux Bioinspires Par L’expression Genique Detection of Patterns of Simulated Bioelectric Activity and Modeling of Bioinspired Neural Networks with Genetic Expression
Modular architecture is a hallmark of many brain circuits. Particularly, in the cerebral cortex it has been observed that reciprocal connections are often present between functionally interconnected areas that are hierarchically organized. Evolutionary development is another distinctive characteristic of living species, even the simplest viruses are capable to adapt to better fit new environmen...
متن کاملReciprocal projections in hierarchically organized evolvable neural circuits affect EEG-like signals.
Modular architecture is a hallmark of many brain circuits. In the cerebral cortex, in particular, it has been observed that reciprocal connections are often present between functionally interconnected areas that are hierarchically organized. We investigate the effect of reciprocal connections in a network of modules of simulated spiking neurons. The neural activity is recorded by means of virtu...
متن کاملFrom Local Chaos to Critical Slowing Down: A Theory of the Functional Connectivity of Small Neural Circuits
Functional connectivity is a fundamental property of neural networks that quantifies the segregation and integration of information between cortical areas. Due to mathematical complexity, a theory that could explain how the parameters of mesoscopic networks composed of a few tens of neurons affect the functional connectivity is still to be formulated. Yet, many interesting problems in neuroscie...
متن کاملNeurobiologically Realistic Determinants of Self-Organized Criticality in Networks of Spiking Neurons
Self-organized criticality refers to the spontaneous emergence of self-similar dynamics in complex systems poised between order and randomness. The presence of self-organized critical dynamics in the brain is theoretically appealing and is supported by recent neurophysiological studies. Despite this, the neurobiological determinants of these dynamics have not been previously sought. Here, we sy...
متن کامل